Meet Your Daily Skincare Heroes
Your three essential steps to a smoother, brighter complexion.
Real People, Real Results | After 8 weeks*
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*Individual results may vary.
GLYCATION: The Hidden Culprit Behind Premature Aging
Patented Supplamine® helps block sugar-induced protein cross-linking that stiffens and dulls skin
Meg 21 supports firmer, more resilient texture by preserving collagen and elastin integrity
Clinically tested to help diminish the appearance of fine lines and restore youthful radiance
From Cancer Research to
Groundbreaking Skincare
MEG 21 was born at the intersection of cutting-edge science and skincare. Developed by Dr. Annette M. Tobia, Ph.D., MEG 21 is rooted in groundbreaking research from the Fox Chase Cancer Center, one of the nation’s leading institutions in medical innovation.
Originally focused on understanding the damaging effects of glycation—a key contributor to skin aging—Dr. Tobia and her team discovered a breakthrough: Supplamine®, the patented anti-glycation technology at the heart of every MEG 21 formula.
Today, MEG 21 brings together advanced science, clinically proven ingredients, and a commitment to skin longevity, offering products that help reduce visible signs of aging, protect against environmental damage, and support healthier, more radiant skin.
The Skincare Standard
We set our standards high, and so should you. Our soothing formulas give your skin exactly what it needs and nothing more.
Bestsellers
From the blog
Discover our latest articles and insights
From Metformin to Supplamine®: The Science of Anti-Glycation Skincare
In recent years, the medical and scientific communities have shown renewed interest in theaging process...
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The Power of Anti-Glycation End (A.G.E.) Skincare: What It Is and Why You Need It
Anti-Glycation End (A.G.E.) skincare—a groundbreaking approach to skincare that addresses one of the lesser-known culprits of skin aging: glycation. In this article, we’ll break down what glycation is, why A.G.E. products are beneficial, and how our line at Meg 21 can help you maintain youthful, radiant skin.
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Supplamine® : Novel Science in Skincare
Supplamine® prevents skin damage in two distinct ways, by: preventing the development of toxic sugars and neutralizing the toxic sugars in our skin from the foods we eat.
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Sugar? No Thanks! The Truth About Glycation
“Sugar and spice and everything nice” is what little girls were said to be made of, which is a lot better than the “snips and snails” that was the stuff of little boys. As a young girl, having sugar as a basic building block may seem fantastic, but when it comes to skin health and aging it is anything but.
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Patented Supplamine®
Clinically Tested
Anti-Glycation Power
A.G.E. Skincare
